The Home and Hospital Center is located in Bare Hills on Falls Road, just north of the Mount Washington area of Baltimore City. The name Bare Hills refers to the lack of trees and the unique vegetation that grows in this area due to deposits of chromium. Historically, the area was settled by freed slaves at the turn of the century. The school building is constructed of serpentine rock that was quarried from the Bare Hills area.

The Home and Hospital Center has fifteen classrooms that are equipped with bridge telephone units and an international teleconferencing platform, which teachers use to conduct teleclasses.  Each class can accommodate from twenty to twenty-six students. The teleclass system allows the teacher to work with students in small groups and to talk privately with individual students.  All classrooms are equipped with computers that are used to enhance teaching and learning. The computer provides a visual component to the lesson and also acts as an interactive blackboard in higher-level math and science courses.